The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 18, 2013
Filed:
Jan. 23, 2009
Marian Hajduch, Moravsky Beroun, CZ;
Marta Dziechciarkova, Olomouc, CZ;
Lenka Radova, Otinoves, CZ;
Marek Svoboda, Syrovice, CZ;
Marian Hajduch, Moravsky Beroun, CZ;
Marta Dziechciarkova, Olomouc, CZ;
Lenka Radova, Otinoves, CZ;
Marek Svoboda, Syrovice, CZ;
Univerzita Palackeho V Olomouci, Lekarska Fakulta, Olomouc, CZ;
Masarykuv Onkologicky Ustav, Brno, CZ;
Abstract
The invention relates to a method for determining the sensitivity of patients suffering from a cancer disease towards targeted biological therapy based on the inhibition of signaling pathways of the members of HER family (e.g., HER-1, HER-2, HER-3 and HER-4) by determining the expression of the biomarker S6 kinase or its post-translationally modified form or of the biomarkers of the activation of S6 kinase or their post-translationally modified forms in the tumor.