The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 18, 2013
Filed:
Aug. 18, 2009
Peter Frank Ekhart, Zwijnaarde, BE;
Hans Van Der Saag, Brussels, BE;
Sam Possemiers, Ghent, BE;
Pieter Van Den Abbeele, Ghent, BE;
Tom Van DE Wiele, Ghent, BE;
Audrey Martine Neyrinck, Louvain-la-Neuve, BE;
Nathalie Maria Nelly Delzenne, Louvain-la-Neuve, BE;
Patrice D Cani, Louvain-la-Neuve, BE;
Peter Frank Ekhart, Zwijnaarde, BE;
Hans Van Der Saag, Brussels, BE;
Sam Possemiers, Ghent, BE;
Pieter Van Den Abbeele, Ghent, BE;
Tom Van De Wiele, Ghent, BE;
Audrey Martine Neyrinck, Louvain-la-Neuve, BE;
Nathalie Maria Nelly Delzenne, Louvain-la-Neuve, BE;
Patrice D Cani, Louvain-la-Neuve, BE;
BioActor B.V., Maastricht, NL;
Abstract
The present invention is directed to a particular arabinoxylan ('AX') preparation and the finding that this preparation has a beneficial effect on the organization of the intestinal microbial community in the lumen and in particular at the site of the gut mucosa, where it modulates the barrier function of the intestinal surface, primarily by modulating the mucosa-associated microbial community towards a relative increase of health beneficial bacteria, such as bifidobacteria and lactobacilli. It is accordingly a first aspect of the present invention to provide said arabinoxylan preparation characterized in comprising isolated water-soluble arabinoxylans and the use thereof to improve functioning (e.g. barrier function) of the intestinal epithelium. Thus, in a further aspect the present invention provides compositions, both pharmaceutical and nutritional compositions, comprising said arabinoxylan preparations; in particular pharmaceuticals, medical foods, food supplements or food compositions, such as infant formula products, dairy products, bakery products or pastry products. The compositions optionally comprise probiotics such asor