The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2013
Filed:
Feb. 19, 2010
Applicants:
Tetsuo Nagano, Tokyo, JP;
Yasuteru Urano, Kanagawa, JP;
Masayo Sakabe, Tokyo, JP;
Inventors:
Assignee:
The University of Tokyo, Toyko, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 313/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
A compound represented by the formula (I) or a salt thereof (Rrepresents hydrogen atom, or a substituent; Rto Rrepresent hydrogen atom, hydroxyl group, an alkyl group, or a halogen atom; Rand Rrepresent hydrogen atom, or an alkyl group; X represents a C-Calkylene group; and Rrepresents an acyl group), which promptly causes a structural change from a non-fluorescent closed ring structure to a strongly fluorescent open ring structure by hydrolysis of an acyl group, and is useful as a fluorescent probe for measuring a protease showing superior suitability for quantification.