The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2013
Filed:
Mar. 05, 2008
Applicants:
Oded Arad, Rehovot, IL;
Elena Ostrovsky, Rishon Le-Zion, IL;
Inventors:
Oded Arad, Rehovot, IL;
Elena Ostrovsky, Rishon Le-Zion, IL;
Assignee:
Chemagis Ltd., Bnei Brak, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides an improved method of chromatographically separating the isomers of (1R,rR)-atracurium salts by high-performance liquid chromatography (HPLC), in the absence of a strong acid. The separation is preferably performed on a silica gel HPLC column using an eluent containing an organic solvent, a polar aprotic co-solvent and a weak organic acid.