The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2013
Filed:
Jul. 17, 2012
Helén Tuvesson Andersson, Lund, SE;
Ulf Vellmar, Södra Sandby, SE;
Ingrid Hallin, Lund, SE;
Leif Svenson, Rydebäck, SE;
Ingela Fritzson, Lund, SE;
Helén Tuvesson Andersson, Lund, SE;
Ulf Vellmar, Södra Sandby, SE;
Ingrid Hallin, Lund, SE;
Leif Svenson, Rydebäck, SE;
Ingela Fritzson, Lund, SE;
Chelsea Therapeutics, Inc., Charlotte, NC (US);
Abstract
Compounds of formula (I) are provided, wherein X is CH═CH, CHO wherein the oxygen atom is bound to ring B, or OCHwherein the oxygen atom is bound to ring A; Y is hydrogen, straight or branched C1-C6 alkyl or a pharmaceutically acceptable inorganic cation; R1 is ethyl or cyclopropyl; and R2 and R3 are the same or different and are selected from F, Cl, Br, CFand OCF. The compounds are useful for the treatment of autoimmune diseases, inflammatory diseases, organ transplant rejection, and malignant neoplasia. Pharmaceutical compositions containing the compounds, methods of using the compounds, and methods for preparing the compounds are also provided.