The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2013
Filed:
Dec. 28, 2007
Applicants:
Bilal Sufi, Santa Clara, CA (US);
Vincent Guerlavais, Arlington, MA (US);
Liang Chen, Discovery Bay, CA (US);
Sanjeev Gangwar, Foster City, CA (US);
Qian Zhang, Danville, CA (US);
David B. Passmore, San Carlos, CA (US);
Inventors:
Bilal Sufi, Santa Clara, CA (US);
Vincent Guerlavais, Arlington, MA (US);
Liang Chen, Discovery Bay, CA (US);
Sanjeev Gangwar, Foster City, CA (US);
Qian Zhang, Danville, CA (US);
David B. Passmore, San Carlos, CA (US);
Assignee:
Medarex, Inc., Princeton, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/10 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61P 35/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present disclosure provides drug-ligand conjugates and drug-cleavable substrate conjugates that are potent cytotoxins. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them.