The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2013
Filed:
Sep. 10, 2004
Geoffrey Paul Smith, Saffron Walden, GB;
David Mark Dunstan Bailey, Saffron Walden, GB;
Raquel Maria Sanches, Saffron Walden, GB;
Harold Swerdlow, Saffron Walden, GB;
David James Earnshaw, Saffron Walden, GB;
Geoffrey Paul Smith, Saffron Walden, GB;
David Mark Dunstan Bailey, Saffron Walden, GB;
Raquel Maria Sanches, Saffron Walden, GB;
Harold Swerdlow, Saffron Walden, GB;
David James Earnshaw, Saffron Walden, GB;
Illumina Cambridge Limited, NR Saffron Walden, GB;
Abstract
The invention relates to modified polymerase enzymes which exhibit improved incorporation of nucleotide analogues bearing substituents at the 3' position of the sugar moiety that are larger in size than the naturally occurring 3′ hydroxyl group. Also described are methods of using the polymerases to incorporate nucleotides into polynucleotides, particularly in the context of DNA sequencing.