The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2013
Filed:
Jul. 07, 2009
Variable domains of camelid heavy-chain antibodies directed against glial fibrillary acidic proteins
Applicants:
Pierre Lafaye, Malakoff, FR;
Jean-pierre Bourgeois, Saint Mande, FR;
Francois Rougeon, Sevres, FR;
Inventors:
Assignee:
Institut Pasteur, Paris, FR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/567 (2006.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to the use of variable domains of camelid heavy-chain antibodies (VHH domains) directed against an intracellular target and having an isoelectric point of at least 8.5, for targeting said intracellular target or for the preparation of a peptide vector. Particularly, it concerns VHH domains directed against a glial fibrillary acidic protein and uses thereof for preparing therapeutic or diagnostic agents.