The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2013

Filed:

Sep. 29, 2010
Applicants:

Karina Yusim, Santa Fe, NM (US);

Bette T. M. Korber, Los Alamos, NM (US);

Carla L. Kuiken, Santa Fe, NM (US);

William M. Fischer, Santa Fe, NM (US);

Inventors:

Karina Yusim, Santa Fe, NM (US);

Bette T. M. Korber, Los Alamos, NM (US);

Carla L. Kuiken, Santa Fe, NM (US);

William M. Fischer, Santa Fe, NM (US);

Assignee:

Los Alamos National Security, LLC, Los Alamos, NM (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/12 (2006.01); A61K 39/29 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to immunogenic compositions useful as HCV vaccines. Provided are HCV mosaic polypeptide and nucleic acid compositions which provide higher levels of T-cell epitope coverage while minimizing the occurrence of unnatural and rare epitopes compared to natural HCV polypeptides and consensus HCV sequences.


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