The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 11, 2013

Filed:

Aug. 31, 2005
Applicants:

Maria Graziella Larm, Rosanna, AU;

Ronald Harding, North Warrandyte, AU;

Michael Johnston, Yarraville, AU;

Albert Zorko Abram, Wantirna, AU;

Prema Vijayakumar, Fremont, CA (US);

Phoebe Sun, Mountain View, CA (US);

Inventors:

Maria Graziella Larm, Rosanna, AU;

Ronald Harding, North Warrandyte, AU;

Michael Johnston, Yarraville, AU;

Albert Zorko Abram, Wantirna, AU;

Prema Vijayakumar, Fremont, CA (US);

Phoebe Sun, Mountain View, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 8/02 (2006.01); A61K 8/00 (2006.01); A61K 31/59 (2006.01); A61K 31/56 (2006.01); A01N 45/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

An oil-in-water microemulsion or sub-micron emulsion composition for dermal delivery of at least one pharmaceutically active ingredient, comprising: a first part including at least one occlusive agent and one or more lipophilic surfactants dispersed throughout a second part including water and at least one hydrophilic surfactant, and a non-surfactant amphiphilic type compound, pharmaceutically active ingredient, and water. It has been found that if a non-surfactant amphiphilic type compound is added together with the second part as would conventionally be the case, a microemulsion or sub-micron emulsion is not formed, by adding the so called third part, phase assembly occurs at a lower temperature than would be expected and moreover, this phase appears to assist in maintaining the microemulsion or sub-micron emulsion characteristics of the formulation during storage at normal temperatures.


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