The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2013
Filed:
Sep. 13, 2010
Catalin Toma, Pittsburgh, PA (US);
Flordeliza Villanueva, Pittsburgh, PA (US);
William Richard Wagner, Wexford, PA (US);
Joon S. Lee, Pittsburgh, PA (US);
Jianjun Wang, Glenshaw, PA (US);
Xucai Chen, Glenshaw, PA (US);
Andrew Fisher, Pittsburgh, PA (US);
Catalin Toma, Pittsburgh, PA (US);
Flordeliza Villanueva, Pittsburgh, PA (US);
William Richard Wagner, Wexford, PA (US);
Joon S. Lee, Pittsburgh, PA (US);
Jianjun Wang, Glenshaw, PA (US);
Xucai Chen, Glenshaw, PA (US);
Andrew Fisher, Pittsburgh, PA (US);
University of Pittsburgh—Of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Abstract
The disclosed technology describes compositions and methods useful for providing cell based therapy. For example, one embodiment of cell based therapy involves the regeneration of injured tissue and/or promoting wound healing. Certain embodiments provide improved therapeutic compositions using microbubbles by delivering biological progenitor cells to the injured tissues. The administration of the microbubbles is directed by acoustic radiation forces that interact with embodiments of microbubbles comprising an acoustically active gas. As such, a high efficiency of progenitor cell delivery to injured tissue is realized. One advantage of this technique over targeted delivery of pharmaceutical compounds, is that the delivered progenitors cells may be derived from the patient (i.e., personalized therapy), thereby avoiding side effects, allergic reactions, and overall problems associated with refractive drug responses.