The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2013
Filed:
Jun. 05, 2012
Dong Wook Kang, Seoul, KR;
Jee Woo Lee, Seoul, KR;
Young Ho Kim, Gyeonggi-do, KR;
Hee Kim, Gyeonggi-do, KR;
Hee Jin Ha, Gyeonggi-do, KR;
Eun Joo Nam, Seoul, KR;
Chan MI Joung, Gyeonggi-do, KR;
Dong Wook Kang, Seoul, KR;
Jee Woo Lee, Seoul, KR;
Young Ho Kim, Gyeonggi-do, KR;
Hee Kim, Gyeonggi-do, KR;
Hee Jin Ha, Gyeonggi-do, KR;
Eun Joo Nam, Seoul, KR;
Chan Mi Joung, Gyeonggi-do, KR;
Daewoong Pharmaceutical Co., Ltd., Gyeonggi-do, KR;
Medifron DBT Co., Ltd., Seoul, KR;
Abstract
The present invention relates to the novel benzofuran derivatives, the preparation thereof and the composition comprising the same. The benzofuran derivatives of the present invention showed potent inhibiting activity of beta-amyloid aggregation and cell cytotoxicity resulting in stimulating the proliferation of neuronal cells as well as recovering activity of memory learning injury caused by neuronal cell injury using transformed animal model with beta-amyloid precursor gene, therefore the compounds can be useful in treating or preventing cognitive function disorder.