The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2013
Filed:
Sep. 17, 2009
Fajun Nan, Shanghai, CN;
Jian Ding, Shanghai, CN;
Jianping Zuo, Shanghai, CN;
Linqian Yu, Shanghai, CN;
Linghua Meng, Shanghai, CN;
Yangming Zhang, Shanghai, CN;
NA Yang, Shanghai, CN;
Min Gu, Shanghai, CN;
Fajun Nan, Shanghai, CN;
Jian Ding, Shanghai, CN;
Jianping Zuo, Shanghai, CN;
Linqian Yu, Shanghai, CN;
Linghua Meng, Shanghai, CN;
Yangming Zhang, Shanghai, CN;
Na Yang, Shanghai, CN;
Min Gu, Shanghai, CN;
Abstract
Rapalogs of formula I, pharmaceutically acceptable salts, pharmaceutical compositions, and preparation methods and uses thereof. The rapalogs have the structure of formula I and can be used as an anti-tumor medicament. Comparing with rapamycin, the rapalogs of the present invention exhibit enhanced water solubility, and improved pharmacological and pharmacokinetic properties by introducing a hydrophilic and polar group such as a hydroxyl.