The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2013
Filed:
Aug. 26, 2009
Liping H. Pettus, Thousand Oaks, CA (US);
Andrew Tasker, Simi Valley, CA (US);
Hui-ling Wang, Thousand Oaks, CA (US);
Bin Wu, Thousand Oaks, CA (US);
Ryan Wurz, Newbury Park, CA (US);
Liping H. Pettus, Thousand Oaks, CA (US);
Andrew Tasker, Simi Valley, CA (US);
Hui-Ling Wang, Thousand Oaks, CA (US);
Bin Wu, Thousand Oaks, CA (US);
Ryan Wurz, Newbury Park, CA (US);
Amgen Inc., Thousand Oaks, CA (US);
Abstract
The present invention comprises a new class of compounds useful for the prophylaxis and treatment of protein kinase mediated diseases, including inflammation and related conditions. The compounds have a general Formula I wherein A, R, R, R, R, R, R, X and n are defined herein. The invention also comprises pharmaceutical compositions including one or more compounds of Formula I, uses of such compounds and compositions for treatment of p38 map kinase mediated diseases including rheumatoid arthritis, psoriasis, chronic obstructive pulmonary disease, pain and other inflammatory disorders, as well as intermediates and processes useful for the preparation of compounds of Formula I.