The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2013
Filed:
Jul. 27, 2009
Jason Katz, Newton Highlands, MA (US);
James Jewell, Somerville, MA (US);
Joon Jung, Newton, MA (US);
Solomon Kattar, Arlington, MA (US);
Yongquan Hou, Cambridge, MA (US);
Rachel Maccoss, Brookline, MA (US);
Satoru Ito, Tsukuba, JP;
Jason Katz, Newton Highlands, MA (US);
James Jewell, Somerville, MA (US);
Joon Jung, Newton, MA (US);
Solomon Kattar, Arlington, MA (US);
Yongquan Hou, Cambridge, MA (US);
Rachel MacCoss, Brookline, MA (US);
Satoru Ito, Tsukuba, JP;
Merck Sharp & Dohme Corp., Rahway, NJ (US);
MSD K.K., Tokyo, JP;
Abstract
The present invention relates to pyrazolopyridines and imidazopyridines which are inhibitors of the kinase PDK1 and are thus useful for the treatment of myeloproliferative disorders or cancer. The compounds are also useful as inhibitors of other kinases such as FGFR3, NTRK3, RP-S6K and WEE1. Furthermore, the present compounds also selectively inhibit microtubule affinity regulating kinase (MARK) and are therefore useful for the treatment or prevention of Alzheimer's disease.