The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2013
Filed:
Oct. 23, 2003
Ernst Torndal Binderup, Taastrup, DK;
Kai Holst Hansen, Herlev, DK;
Claus Aage Svensgaard Bretting, Frederiksberg, DK;
Martin John Calverley, Herlev, DK;
Ernst Torndal Binderup, Taastrup, DK;
Kai Holst Hansen, Herlev, DK;
Claus Aage Svensgaard Bretting, Frederiksberg, DK;
Martin John Calverley, Herlev, DK;
Leo Pharma A/S, Ballerup, DK;
Abstract
Compounds according to formula I in which formula R1 and R2, which may be the same or different, represent halogen, (C-C)hydrocarbyl, optionally substituted with one or two hydroxyl group or one or more fluorine atoms, or, together with the carbon atom to which they are both attached, R1 and R2 form a (C-C)carbocyclic ring, or one of R1 and R2 taken together with R3 forms a direct bond, such that a triple bond is constituted, or R1 and R2 represent both hydrogen; R3 when not forming a direct bond with one of R1 and R2 represents hydrogen or (C-C)hydrocarbyl; X represents (E)-ethylene, (Z)-ethylene, ethynylene, or a bond; Y and Z independently represent hydrogen or methyl; and prodrugs and stereo isomeric forms thereof are provided together with their use in therapy, and their use in the manufacture of medicaments.