The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2013
Filed:
Mar. 31, 2011
Marjorie Robbins, Vancouver, CA;
Susan DE Jong, Vancouver, CA;
Vandana Sood, Vancouver, CA;
Lisa E. Hensley, Frederick, MD (US);
Ian Maclachlan, Mission, CA;
Marjorie Robbins, Vancouver, CA;
Susan de Jong, Vancouver, CA;
Vandana Sood, Vancouver, CA;
Lisa E. Hensley, Frederick, MD (US);
Ian MacLachlan, Mission, CA;
Protiva Biotherapeutics, Inc., Burnaby, BC, CA;
The United States Army Medical Research and Materiel Command, Washington, DC (US);
Abstract
The present invention provides compositions comprising therapeutic nucleic acids such as interfering RNA (e.g., dsRNA such as siRNA) that target Lassa virus (LASV) or tissue factor (TF) gene expression, lipid particles comprising one or more (e.g., a cocktail) of the therapeutic nucleic acids, methods of making the lipid particles, and methods of delivering and/or administering the lipid particles (e.g., for treating hemorraghic fever).