The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2013
Filed:
Apr. 30, 2010
Hiroyuki Aburatani, Tokyo, JP;
Lilin Zhang, Tokyo, JP;
Keisuke Ishii, Tokyo, JP;
Katsushi Kouda, Tokyo, JP;
Aya Sakamoto, Tokyo, JP;
Keiko Katsumi, Tokyo, JP;
Hiroshi Onishi, Tokyo, JP;
Yoko Kayukawa, Tokyo, JP;
Hiroyuki Aburatani, Tokyo, JP;
Lilin Zhang, Tokyo, JP;
Keisuke Ishii, Tokyo, JP;
Katsushi Kouda, Tokyo, JP;
Aya Sakamoto, Tokyo, JP;
Keiko Katsumi, Tokyo, JP;
Hiroshi Onishi, Tokyo, JP;
Yoko Kayukawa, Tokyo, JP;
The University of Tokyo, Tokyo, JP;
Perseus Proteomics Inc., Tokyo, JP;
Abstract
It is an object of the present invention to provide an anti-cadherin antibody having high antibody-dependent cellular cytotoxicity. The present invention provides an anti-cadherin antibody, which recognizes any one of an upstream region of EC1, a cadherin domain 4 (EC4) and a cadherin domain 5 (EC5), wherein an antibody-dependent cellular cytotoxicity at an antibody concentration of 1 μg/mL is 30% or more.