The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2013
Filed:
Dec. 02, 2008
Allan Svendsen, Hoersholm, DK;
Lars Beier, Lyngby, DK;
Signe Eskildsen Larsen, Lyngby, DK;
Thomas Lenhard, Lyngby, DK;
Tanja Maria Rosenkilde Kjaer, Holte, DK;
Peter Colin Gregory, Hannover, DE;
Allan Svendsen, Hoersholm, DK;
Lars Beier, Lyngby, DK;
Signe Eskildsen Larsen, Lyngby, DK;
Thomas Lenhard, Lyngby, DK;
Tanja Maria Rosenkilde Kjaer, Holte, DK;
Peter Colin Gregory, Hannover, DE;
Novozymes A/S, Bagsvaerd, DK;
Solvay Pharmaceuticals, GmbH, Hannover, DE;
Abstract
The invention relates to novel variants of a protease derived fromsp. (SEQ ID NO: 1) and closely related proteases, as well as their pharmaceutical use. The variants show improved performance in the treatment of pancreatic exocrine insufficiency (PEI). The variants may be combined with a lipase and/or an amylase. Other examples of medical indications are: Treatment of digestive disorders, pancreatitis, cystic fibrosis, diabetes type I, and/or diabetes type II.