The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 04, 2013

Filed:

Sep. 10, 2008
Applicants:

Mark Jaroszeski, Wesley Chapel, FL (US);

Gabriel A. Lopez-diaz, Wesley Chapel, FL (US);

Richard J. Connolly, Riverview, FL (US);

Andrew M. Hoff, Tampa, FL (US);

Inventors:

Mark Jaroszeski, Wesley Chapel, FL (US);

Gabriel A. Lopez-Diaz, Wesley Chapel, FL (US);

Richard J. Connolly, Riverview, FL (US);

Andrew M. Hoff, Tampa, FL (US);

Assignee:

University of South Florida, Tampa, FL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 13/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method for facilitating a delivery of a molecule into an interior space of a cell includes the steps of introducing a molecule into a biological structure comprising a cell and applying a substantially continuous low-level electric field, in the form of non-thermal plasma (ionized gas) generated by a direct current voltage applied to an electrode, to the molecule and biological structure. The field is applied for a duration sufficient to effect a change in porosity the cell of the biological structure sufficient to facilitate an entry of a desired molecule into an interior thereof.


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