The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 28, 2013

Filed:

Dec. 16, 2008
Applicants:

Malcolm Francis Graham Stevens, Loughborough, GB;

David Cousin, Sneinton, GB;

Sharon Jennings, Leicester, GB;

Andrew James Mccarroll, Sneinton, GB;

John Gareth Williams, Nottingham, GB;

Marc Geoffery Hummersone, Nottingham, GB;

Jihong Zhang, Nottingham, GB;

Inventors:

Malcolm Francis Graham Stevens, Loughborough, GB;

David Cousin, Sneinton, GB;

Sharon Jennings, Leicester, GB;

Andrew James McCarroll, Sneinton, GB;

John Gareth Williams, Nottingham, GB;

Marc Geoffery Hummersone, Nottingham, GB;

Jihong Zhang, Nottingham, GB;

Assignee:

Pharminox Limited, Nottingham, GB;

Attorney:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 519/00 (2006.01); C07F 7/10 (2006.01); C07F 9/141 (2006.01); A61K 31/395 (2006.01); A61K 31/4188 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain 3-substituted-4-oxo-3,4-dihydro-imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid amide (collectively referred to herein as 3TM compounds). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit cell proliferation, and in the treatment of proliferative disorders such as cancer, etc., and methods of preparing such compounds.


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