The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2013
Filed:
Jan. 13, 2011
Applicants:
Shi Du Yan, Tenafly, NJ (US);
David M. Stern, Cincinnati, OH (US);
Joyce W. Lustbader, Tenafly, NJ (US);
Hao Wu, New York, NY (US);
Inventors:
Shi Du Yan, Tenafly, NJ (US);
David M. Stern, Cincinnati, OH (US);
Joyce W. Lustbader, Tenafly, NJ (US);
Hao Wu, New York, NY (US);
Assignee:
The Trustees of Columbia University in the City of New York, New York, NY (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 2/00 (2006.01); C07K 4/00 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
This invention provides methods, compositions and articles of manufacture for inhibiting binding between Aβ protein and ABAD in cells. Uses of this invention include, for example, treating Alzheimer's disease; reducing free radical generation, DNA fragmentation, and cytochrome C release in cells; and preserving cell viability by preventing LDH release from a cell.