The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2013
Filed:
Feb. 05, 2010
Hing L. Sham, Palo Alto, CA (US);
Roy K. Hom, San Francisco, CA (US);
Andrei W. Konradi, Burlingame, CA (US);
Gary D. Probst, San Francisco, CA (US);
Simeon Bowers, Oakland, CA (US);
Anh Truong, Burlingame, CA (US);
R. Jeffrey Neitz, San Francisco, CA (US);
Jennifer Sealy, Oakland, CA (US);
Gergely Toth, Palo Alto, CA (US);
Hing L. Sham, Palo Alto, CA (US);
Roy K. Hom, San Francisco, CA (US);
Andrei W. Konradi, Burlingame, CA (US);
Gary D. Probst, San Francisco, CA (US);
Simeon Bowers, Oakland, CA (US);
Anh Truong, Burlingame, CA (US);
R. Jeffrey Neitz, San Francisco, CA (US);
Jennifer Sealy, Oakland, CA (US);
Gergely Toth, Palo Alto, CA (US);
Elan Pharmaceuticals, Inc., South San Francisco, CA (US);
Abstract
The present disclosure provides inhibitors of c-Jun N-terminal kinases (JNK) having a structure according to the following formula: or a salt or solvate thereof, wherein ring A, C, C, Z, R, W and Cy are defined herein. The disclosure further provides pharmaceutical compositions including the compounds of the present disclosure and methods of making and using the compounds and compositions of the present disclosure, e.g., in the treatment and prevention of various disorders, such as Alzheimer's disease.