The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 28, 2013

Filed:

Sep. 22, 2009
Applicants:

Michael K. C. Wong, Somerset, NJ (US);

Wensheng Yu, Edison, NJ (US);

Ling Tong, Warren, NJ (US);

Brian J. Lavey, New Providence, NJ (US);

Bandarpalle B. Shankar, Branchburg, NJ (US);

Joseph A. Kozlowski, Princeton, NJ (US);

Seong Heon Kim, Livington, NJ (US);

Guowei Zhou, Somerset, NJ (US);

De-yi Yang, Morris Plains, NJ (US);

Razia K. Rizvi, Bloomfield, NJ (US);

Lei Chen, Roselle Park, NJ (US);

Aneta Maria Kosinzki, South Amboy, NJ (US);

Kristin E. Rosner, Watertown, NJ (US);

Luke Fire, Cambridge, MA (US);

Judson E. Richard, Kittery, ME (US);

Dansu LI, Reading, MA (US);

Inventors:

Michael K. C. Wong, Somerset, NJ (US);

Wensheng Yu, Edison, NJ (US);

Ling Tong, Warren, NJ (US);

Brian J. Lavey, New Providence, NJ (US);

Bandarpalle B. Shankar, Branchburg, NJ (US);

Joseph A. Kozlowski, Princeton, NJ (US);

Seong Heon Kim, Livington, NJ (US);

Guowei Zhou, Somerset, NJ (US);

De-Yi Yang, Morris Plains, NJ (US);

Razia K. Rizvi, Bloomfield, NJ (US);

Lei Chen, Roselle Park, NJ (US);

Aneta Maria Kosinzki, South Amboy, NJ (US);

Kristin E. Rosner, Watertown, NJ (US);

Luke Fire, Cambridge, MA (US);

Judson E. Richard, Kittery, ME (US);

Dansu Li, Reading, MA (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4166 (2006.01); A61K 31/4178 (2006.01); C07D 233/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to compounds of the Formula (I)-(IX):, as defined herein, or a pharmaceutically acceptable salt, solvate or ester thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF-α combinations thereof.


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