The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2013
Filed:
Mar. 21, 2011
Adnan M. M. Mjalli, Oak Ridge, NC (US);
Anitha Hari, High Point, NC (US);
Bapu Gaddam, High Point, NC (US);
Devi Reddy Gohimukkula, Jamestown, NC (US);
Dharma Rao Polisetti, High Point, NC (US);
Mohan Rao, Greensboro, NC (US);
Raju Bore Gowda, Oak Ridge, NC (US);
Robert Carl Andrews, Jamestown, NC (US);
Rongyuan Xie, Greensboro, NC (US);
Soumya P. Sahoo, Greensboro, NC (US);
Tan Ren, Colfax, NC (US);
William Kenneth Banner, Greensboro, NC (US);
Adnan M. M. Mjalli, Oak Ridge, NC (US);
Anitha Hari, High Point, NC (US);
Bapu Gaddam, High Point, NC (US);
Devi Reddy Gohimukkula, Jamestown, NC (US);
Dharma Rao Polisetti, High Point, NC (US);
Mohan Rao, Greensboro, NC (US);
Raju Bore Gowda, Oak Ridge, NC (US);
Robert Carl Andrews, Jamestown, NC (US);
Rongyuan Xie, Greensboro, NC (US);
Soumya P. Sahoo, Greensboro, NC (US);
Tan Ren, Colfax, NC (US);
William Kenneth Banner, Greensboro, NC (US);
High Point Pharmaceuticals, LLC, High Point, NC (US);
Abstract
The present invention provides substituted imidazo[1,2-b]pyridazine derivatives, pharmaceutically acceptable salts thereof, and tautomers of any of the foregoing, where such compounds inhibit β-site amyloid precursor protein-cleaving enzyme (BACE), which may be useful in the treatment of diseases in which BACE is involved, such as Alzheimer's disease. The invention also provides pharmaceutical compositions comprising any of these compounds and the use of any of these compounds and compositions in the treatment of diseases, disorders, or conditions in which BACE is involved.