The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 21, 2013

Filed:

Nov. 24, 2009
Applicants:

Subhash Chandra Taneja, Jammu Tawi, IN;

Mushtaq Ahmad Aga, Jammu Tawi, IN;

Brijesh Kumar, Jammu Tawi, IN;

Vijay Kumar Sethi, Jammu Tawi, IN;

Samar Singh Andotra, Jammu Tawi, IN;

Ghulam Nabi Qazi, Jammu Tawi, IN;

Inventors:

Subhash Chandra Taneja, Jammu Tawi, IN;

Mushtaq Ahmad Aga, Jammu Tawi, IN;

Brijesh Kumar, Jammu Tawi, IN;

Vijay Kumar Sethi, Jammu Tawi, IN;

Samar Singh Andotra, Jammu Tawi, IN;

Ghulam Nabi Qazi, Jammu Tawi, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/12 (2006.01); C07D 471/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a facile, highly efficient and economical process for the preparation of optically active N-benzyl-3-hydroxypyrrolidine in high yield from a naturally occurring alkaloid vasicine. The natural alkaloid vasicine is used as a precursor of (S)—N-benzyl-3-hydroxypyrrolidine and (R)—N-benzyl-3-hydroxypyrrolidines which can easily be sourced from the medicinal plant Adatoda vasica by the method known in the art and transformed to optical isomers (R) and (S)—N-benzyl-3-hydroxypyrrolidine by the method described in the present invention.


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