The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8445687 B1

PDF
Full Text
Expired
Date of Patent:
May. 21, 2013

Filed:

Sep. 10, 2008
Applicants:

Dharmaraj Ramachandra Rao, Maharashtra, IN;

Rajendra Narayanrao Kankan, Maharashtra, IN;

Maruti Ghagare, Maharashtra, IN;

Sandip Chikhalikar, Mumbai, IN;

Inventors:

Dharmaraj Ramachandra Rao, Maharashtra, IN;

Rajendra Narayanrao Kankan, Maharashtra, IN;

Maruti Ghagare, Maharashtra, IN;

Sandip Chikhalikar, Mumbai, IN;

Assignee:

Cipla Limited, Mumbai, IN;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 213/81 (2006.01); A61K 31/44 (2006.01);
U.S. Cl.
CPC ...
Abstract

There is provided a process for preparing sorafenib or a salt thereof comprising the use of a compound of formula (A) wherein R' is selected from the group consisting of hydrogen, —C(O)OA, —C(O)CX, —C(O)NH, —C(O)—NHOH or There is also provided intermediate compounds of general formula (A), N-methyl-4-(4-ureidophenoxy)picolinamide, 4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenylcarbamate derivative and N-methyl-4-(4-(2,2,2-trihaloacetamido)phenoxy)picolinamide, processes for their preparation and their use in the preparation of sorafenib.


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Rao, Dharmaraj. (2013). Process for the preparation of a raf kinase inhibitor and intermediates for use in the process (U.S. Patent No. 8445687). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8445687

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