The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 2013
Filed:
Oct. 29, 2008
Minako Hoshi, Kyoto, JP;
Michio Sato, Tokyo, JP;
Shoji Ideno, Osaka, JP;
Koji Naito, Osaka, JP;
Satoshi Horie, Osaka, JP;
Munehiro Noda, Osaka, JP;
Hajime Horii, Osaka, JP;
Minako Hoshi, Kyoto, JP;
Michio Sato, Tokyo, JP;
Shoji Ideno, Osaka, JP;
Koji Naito, Osaka, JP;
Satoshi Horie, Osaka, JP;
Munehiro Noda, Osaka, JP;
Hajime Horii, Osaka, JP;
Tao Health Life Pharma Co., Ltd., Kyoto, JP;
Abstract
An antibody provided by the present invention has a low reactivity with amyloid precursor proteins, and has a higher reactivity with amylospheroids than with amyloid β fibrils or monomeric amyloid β-proteins. According to the present invention, an antibody is provided that has a higher reactivity with amylospheroids than with amyloid precursor proteins, and has any one or more of the following properties: (i) a higher activity with amylospheroids than with amyloid β fibrils; (ii) a higher reactivity with amylospheroids than with monomeric amyloid β-proteins; and (iii) an activity of inhibiting neuronal cell death induced by amylospheroids.