The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 21, 2013

Filed:

Apr. 11, 2007
Applicants:

Jeffrey a Medin, North York, CA;

Joshua Daniel Silvertown, Toronto, CA;

Alastair J. S. Summerlee, Guelph, CA;

Inventors:

Jeffrey A Medin, North York, CA;

Joshua Daniel Silvertown, Toronto, CA;

Alastair J. S. Summerlee, Guelph, CA;

Assignee:

Armour Therapeutics Inc., Toronto, Ontario, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Modified H2 relaxms which act as antagonists of the relaxm receptor in cells and tissues, in particular, modified H2 relaxms comprising one or more alterations of the ammo acid sequence at positions B 13, B17 and B20 located in the receptor binding domain The antagonists retain affinity to the receptor, but do not substantially activate the receptor once bound thereto The H2 relaxm antagonists are used in compositions and methods for the treatment of cancers wherein a relaxm receptor is expressed.


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