The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 2013
Filed:
Apr. 13, 2009
Applicants:
Shaomeng Wang, Saline, MI (US);
Haiying Sun, Ann Arbor, MI (US);
Zaneta Nikolovska-coleska, Ann Arbor, MI (US);
Inventors:
Shaomeng Wang, Saline, MI (US);
Haiying Sun, Ann Arbor, MI (US);
Zaneta Nikolovska-Coleska, Ann Arbor, MI (US);
Assignee:
The Regents of the University of Michigan, Ann Arbor, MI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01); C07D 403/02 (2006.01); C07D 235/06 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates to heteroaryl-substituted bicyclic mimetics of Smac which function as inhibitors of Inhibitor of Apoptosis Proteins. The invention also relates to the use of these mimetics for inducing apoptotic cell death and for sensitizing cells to inducers of apoptosis.