The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 21, 2013

Filed:

Nov. 15, 2010
Applicants:

Richard Penn, Chicago, IL (US);

Pia Runeberg-roos, Esbo, FI;

Maxim M. Bespalov, Helsinki, FI;

Mart Saarma, Helsinki, FI;

Inventors:

Richard Penn, Chicago, IL (US);

Pia Runeberg-Roos, Esbo, FI;

Maxim M. Bespalov, Helsinki, FI;

Mart Saarma, Helsinki, FI;

Assignees:

NTF Therapeutics Inc, St. Paul, MN (US);

University of Helsinki, Helsinki, FI;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/22 (2006.01); A61P 3/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Neurturin polypeptides which possess reduced heparin and heparan sulfate binding affinity but retain neurotrophic activity, nucleic acids which encode the neurturin variants and vectors and host cells which express the enhanced neurturin polypeptides. Use of the enhanced neurturin polypeptides, nucleic acids and host cells in the treatment or prevention of disease.


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