The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 2013
Filed:
Sep. 24, 2008
Thomas Neumann, Seattle, WA (US);
Anna Tourovskaia, Mountlake Terrace, WA (US);
Mark E. Fauver, Seattle, WA (US);
Julia Oi Yan Yu, Kirkland, WA (US);
Thomas Neumann, Seattle, WA (US);
Anna Tourovskaia, Mountlake Terrace, WA (US);
Mark E. Fauver, Seattle, WA (US);
Julia Oi Yan Yu, Kirkland, WA (US);
Nortis, Inc., Seattle, WA (US);
Abstract
A method for creating networks of perfusable microvessels in vitro. Cells including cell types capable of sprouting are seededinto a channel in a matrix at to activate competencyof the cells for sprouting as microvessels based on the seeding density. The matrix channel is perfused with medium to allow parent vessels to form and for viability. The parent vessels and matrix are incubated and perfused to provide for sprouting of microvessels from parent vessels into the surrounding matrix. The sprouting parent vessels are grown until network forms