The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 21, 2013
Filed:
Sep. 05, 2012
Ming-hsi Huang, Miaoli County, TW;
Pele Choi-sing Chong, Miaoli County, TW;
Chih-hsiang Leng, Miaoli County, TW;
Shih-jen Liu, Miaoli County, TW;
Hsin-wei Chen, Miaoli County, TW;
Ming-Hsi Huang, Miaoli County, TW;
Pele Choi-Sing Chong, Miaoli County, TW;
Chih-Hsiang Leng, Miaoli County, TW;
Shih-Jen Liu, Miaoli County, TW;
Hsin-Wei Chen, Miaoli County, TW;
National Health Research Institutes, Miaoli County, TW;
Abstract
A method for enhancing a body's response to an immunogen is disclosed. The method comprises immunizing a subject in need thereof a vaccine composition in a water-in-oil (W/O/W) emulsion that comprises (a) an antigen; and (b) an adjuvant composition in a W/O/W emulsion. The adjuvant composition comprises: (i) a continuous aqueous phase comprising HO; (ii) an oil phase comprising oil dispersed in the continuous aqueous phase, comprising an internal aqueous phase comprising HO, being dispersed in the oil phase; and a physiologically acceptable lipophilic emulsifier selected from the group consisting of mannide monooleate and sorbitan esters, stabilizing the interface between the inner aqueous phase and the oil phase to form a water-in-oil (W/O) emulsion; and (iii) poly(ethylene glycol)-block-poly(lactide-co-ε-caprolactone), stabilizing the interface between the oil phase and the continuous aqueous phase.