The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8444964 B1

PDF
Full Text
Expired
Date of Patent:
May. 21, 2013

Filed:

Jul. 11, 2002
Applicants:

Fakhrai Habib, La Jolla, CA (US);

Dorigo Oliver, San Diego, CA (US);

Sobol E Robert, La Jolla, CA (US);

Inventors:

Fakhrai Habib, La Jolla, CA (US);

Dorigo Oliver, San Diego, CA (US);

Sobol E Robert, La Jolla, CA (US);

Assignee:

Novarx, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/09 (2010.01); C12N 5/10 (2006.01); C07H 21/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides a method of preventing or reducing the severity of a cancer in a subject by stimulating the subject's immune response against the cancer. The invention provides, for example, a method of stimulating an immune response in a subject by administering to the subject tumor cells that are substantially similar to the subject's cancer cells and that are genetically modified to reduce or inhibit the expression of one or more immunosuppressive agents. The invention also provides a method of preventing or reducing the severity of cancer in a subject by stimulating the subject's immune response against the cancer by administering to the subject tumor cells that are substantially similar to the subject's cancer cells and that are genetically modified to prevent the expression of an immunosuppressive agents and, in combination with the genetically modified tumor cells, an immunostimulatory agent. The invention further provides compositions useful for practicing the claimed methods.


Find Patent Forward Citations

Habib, Fakhrai. (2013). Compositions and methods for enhanced tumor cell immunity in vivo (U.S. Patent No. 8444964). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8444964

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…