The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2013
Filed:
Feb. 28, 2011
Éric Marsault, Québec, CA;
Kamel Benakli, Blue Bell, PA (US);
Hamid R. Hoveyda, Brussels, BE;
Mark L. Peterson, Québec, CA;
Sylvie Beaubien, Sherbrooke, CA;
Luc Ouellet, Québec, CA;
Carl St-louis, Québec, CA;
Sophie Beauchemin, Québec, CA;
Éric Marsault, Québec, CA;
Kamel Benakli, Blue Bell, PA (US);
Hamid R. Hoveyda, Brussels, BE;
Mark L. Peterson, Québec, CA;
Sylvie Beaubien, Sherbrooke, CA;
Luc Ouellet, Québec, CA;
Carl St-Louis, Québec, CA;
Sophie Beauchemin, Québec, CA;
Tranzyme Pharma, Inc., , CA;
Abstract
Novel spatially-defined macrocyclic compounds containing specific conformational control elements are disclosed. Libraries of these macrocycles are then used to select one or more macrocycle species that exhibit a specific interaction with a particular biological target. In particular, compounds according to the invention are disclosed as agonists or antagonists of a mammalian motilin receptor and a mammalian ghrelin receptor.