The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 2013

Filed:

Feb. 05, 2009
Applicants:

Fabrice Agou, Paris, FR;

Jeanne Chiaravalli, Paris, FR;

Stéphane Duquerroy, Paris, FR;

Elisabeth Fontan, Boulogne, FR;

Olivera Grubisha, Surrey, GB;

Monika Dorota Kaminska, Le Plessis Robinson, FR;

Michel Veron, Paris, FR;

Florence Cordier, Aix les Bains, FR;

Inventors:

Fabrice Agou, Paris, FR;

Jeanne Chiaravalli, Paris, FR;

Stéphane Duquerroy, Paris, FR;

Elisabeth Fontan, Boulogne, FR;

Olivera Grubisha, Surrey, GB;

Monika Dorota Kaminska, Le Plessis Robinson, FR;

Michel Veron, Paris, FR;

Florence Cordier, Aix les Bains, FR;

Assignees:

Les Laboratoires Servier, Suresnes Cedex, FR;

Institut Pasteur, Paris Cedex, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01); G01N 31/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to a crystal of the CC2-LZ domain of the NEMO protein, in which the three-dimensional structure has been determined by X-ray diffraction at a resolution of about 3.25 A. The invention also relates to methods for the crystallization of the CC2-LZ domain. The CC2-LZ crystals and the information derived from the crystalline structures thereof are used for identifying and designing compounds interacting with CC2-LZ.


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