The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2013
Filed:
Sep. 16, 2005
Susan L. Lindquist, Chestnut Hill, MA (US);
Tiago Outeiro, Cambridge, MA (US);
Richard Labaudinière, Sherborn, MA (US);
Susan L. Lindquist, Chestnut Hill, MA (US);
Tiago Outeiro, Cambridge, MA (US);
Richard Labaudinière, Sherborn, MA (US);
Whitehead Institute for Biomedical Research, Cambridge, MA (US);
FoldRx Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
Compounds and compositions are provided for treatment or amelioration of one or more symptoms of α-synuclein toxicity, α-synuclein mediated diseases or diseases in which α-synuclein fibrils are a symptom or cause of the disease. In one embodiment, the compounds for use in the compositions and methods are heteroaryl acylguanidines, heteroarylhydrazones, dihydropyridones, heteroaryl and aryl styryl ketones, and heteroarylpyrazoles.