The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 2013

Filed:

Mar. 02, 2012
Applicants:

David John Augeri, Princeton, NJ (US);

Jeffrey Thomas Bagdanoff, Martinez, CA (US);

Simon David Peter Baugh, Ringoes, NJ (US);

Marianne Carlsen, Yardley, PA (US);

Kenneth Gordon Carson, Princeton, NJ (US);

John Anthony Gilleran, Bridgewater, NJ (US);

Wei He, Lawrenceville, NJ (US);

Tamas Oravecz, The Woodlands, TX (US);

Konstantin Salojin, Conroe, TX (US);

Leonard Sung, Hopewell, NJ (US);

Inventors:

David John Augeri, Princeton, NJ (US);

Jeffrey Thomas Bagdanoff, Martinez, CA (US);

Simon David Peter Baugh, Ringoes, NJ (US);

Marianne Carlsen, Yardley, PA (US);

Kenneth Gordon Carson, Princeton, NJ (US);

John Anthony Gilleran, Bridgewater, NJ (US);

Wei He, Lawrenceville, NJ (US);

Tamas Oravecz, The Woodlands, TX (US);

Konstantin Salojin, Conroe, TX (US);

Leonard Sung, Hopewell, NJ (US);

Assignee:

Lexicon Pharmaceuticals, Inc., The Woodlands, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 495/04 (2006.01); A61K 31/4418 (2006.01); A61K 31/444 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds for the inhibition of mammalian Ste20-like kinase 1 (MST1) are disclosed, along with compositions comprising them and methods of their use in the treatment, management or prevention of an inflammatory or autoimmune diseases or disorders. Particular compounds are of the formula:


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