The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2013
Filed:
Jan. 03, 2008
Peidong Yang, El Cerrito, CA (US);
Rohit Karnik, Cambridge, MA (US);
Kenneth Castelino, Berkeley, CA (US);
Rong Fan, Pasadena, CA (US);
Arun Majumdar, Orinda, CA (US);
Peidong Yang, El Cerrito, CA (US);
Rohit Karnik, Cambridge, MA (US);
Kenneth Castelino, Berkeley, CA (US);
Rong Fan, Pasadena, CA (US);
Arun Majumdar, Orinda, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
A functionalized nanofluidic channel and method for functionalization that provides control over the ionic environment and geometry of the nanofluidic channel with the immobilization of biomolecules on the inner surface of the channel and use of high ionic concentration solutions. In one embodiment, the surface charge of the nanochannel is controlled with the immobilization of a protein such as streptavidin in the nanochannel. In another embodiment, the biomolecules are receptors and changes in nanochannel conductance indicates ligand binding events. The functionalized nanofluidic channel can be easily adapted for use with microchannel arrays.