The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 2013
Filed:
May. 13, 2009
Nisha Palackal, Ann Arbor, MI (US);
Jeffrey K. Johnson, Ann Arbor, MI (US);
Karie L. Mcgowan, Manchester, MI (US);
Kirk W. Maxey, Ann Arbor, MI (US);
Gregory W. Endres, Saline, MI (US);
Nisha Palackal, Ann Arbor, MI (US);
Jeffrey K. Johnson, Ann Arbor, MI (US);
Karie L. McGowan, Manchester, MI (US);
Kirk W. Maxey, Ann Arbor, MI (US);
Gregory W. Endres, Saline, MI (US);
Cayman Chemical Company, Incorporated, Ann Arbor, MI (US);
Abstract
An exemplary embodiment may be directed to a fluorescence polarization assay that screens compounds or agents for their affinity to hematopoietic prostaglandin D synthase (H-PGDS) based on their ability to displace a fluorophore-containing detection analyte bound to an enzyme comprising the primary amino acid sequence of H-PGDS. Another exemplary embodiment utilizes an enzyme having a maltose binding protein amino-acid sequence fused with an N-terminus of the enzyme.