The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 14, 2013

Filed:

Nov. 01, 2007
Applicants:

Rudolf Valenta, Theresienfeld, AT;

Susanne Vrtala, Vienna, AT;

Sabine Stumvoll, St. Peter, AT;

Hans Grönlund, Lidingö, SE;

Monika Grote, Münster, DE;

Luca Vangelista, Padua, IT;

Annalisa Pastore, London, GB;

Wolfgang R. Sperr, Vienna, AT;

Peter Valent, Vienna, AT;

Dietrich Kraft, Vienna, AT;

Inventors:

Rudolf Valenta, Theresienfeld, AT;

Susanne Vrtala, Vienna, AT;

Sabine Stumvoll, St. Peter, AT;

Hans Grönlund, Lidingö, SE;

Monika Grote, Münster, DE;

Luca Vangelista, Padua, IT;

Annalisa Pastore, London, GB;

Wolfgang R. Sperr, Vienna, AT;

Peter Valent, Vienna, AT;

Dietrich Kraft, Vienna, AT;

Assignee:

Phadia AB, Uppsala, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/35 (2006.01); A61K 39/36 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods for desensitization of a mammal suffering from IgE mediated allergy comprise the steps of: administering to said mammal a therapeutically effective amount of an immunogenic and hypoallergenic composition which comprises (i) a Phl p 6 molecule having an N-terminal truncation which makes the molecule at least lack IgE binding capacity, and/or (ii) a Phl p 6 molecule having a C-terminal truncation which makes the molecule at least lack IgE binding capacity, wherein the molecules of (i) and (ii), if employed in combination, together span the complete sequence of Phl p 6, and a pharmaceutically acceptable carrier.


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