The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 2013
Filed:
Dec. 03, 2009
Koji Kawakami, Kyoto, JP;
Masayuki Kohno, Kyoto, JP;
Tomohisa Horibe, Kyoto, JP;
Oumi Nakajima, Kyoto, JP;
Mari Haramoto, Kyoto, JP;
Liying Yang, Kyoto, JP;
Koji Kawakami, Kyoto, JP;
Masayuki Kohno, Kyoto, JP;
Tomohisa Horibe, Kyoto, JP;
Oumi Nakajima, Kyoto, JP;
Mari Haramoto, Kyoto, JP;
Liying Yang, Kyoto, JP;
Other;
Abstract
It is an object of the present invention to provide a substance usable as an anticancer agent or DDS, which has intracellular stability, which is capable of evading side effects from functional disorder with respect to normal cells, or which has instantaneous effect. The inventors developed a novel chimeric peptide targeting cancer cells which overexpress EGFR or the like using a binding peptide such as a peptide sequence binding to EGFR, and a lytic peptide sequence, thereby solving such an object. Particularly, by using a chimeric peptide including an EGF receptor-binding peptide or the like and a cytotoxic peptide, this object was solved.