The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 07, 2013

Filed:

Jun. 29, 2007
Applicants:

Jayne Elizabeth Curry, Cambridge, GB;

Neil James Gallagher, Basel, CH;

John Francis Lyons, London, GB;

Neil Thomas Thompson, Cambridge, GB;

Inventors:

Jayne Elizabeth Curry, Cambridge, GB;

Neil James Gallagher, Basel, CH;

John Francis Lyons, London, GB;

Neil Thomas Thompson, Cambridge, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/56 (2006.01); A61K 31/535 (2006.01); A61K 31/52 (2006.01); A61K 31/44 (2006.01); A61K 31/445 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides combinations of an ancillary compound and a compound which is a salt of 1-cyclopropyl-3-[3-(5-morpholin-4-ylmethyl-1H-benzoimidazol-2-yl)-1H-pyrazol-4-yl]-urea selected from the lactate and citrate salts and mixtures thereof. Also provided are crystalline forms of the salts, methods for making the salts and their uses in treating cancers. The invention further provides combinations of an ancillary compound and a compound of the formula (I) as defined in PCT/GB2004/002824 (WO 2005/002552) or a compound of the formula (I') or a salt, solvate, tautomer or N-oxide thereof, wherein R, E, A and M are as defined in the claims.


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