The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 2013
Filed:
Feb. 11, 2011
Hendrik J. Schuurman, Charlestown, MA (US);
Emanuele Luigi Maria Cozzi, Padua, IT;
Francoise Richard, St. Louis, FR;
Guy Taccard, Hegenheim, FR;
David James Graham White, Cambridge, GB;
Peter John Friend, Oxford, GB;
John Wallwork, Cambridge, GB;
Paolo Brenner, Neuried, DE;
Hendrik J. Schuurman, Charlestown, MA (US);
Emanuele Luigi Maria Cozzi, Padua, IT;
Francoise Richard, St. Louis, FR;
Guy Taccard, Hegenheim, FR;
David James Graham White, Cambridge, GB;
Peter John Friend, Oxford, GB;
John Wallwork, Cambridge, GB;
Paolo Brenner, Neuried, DE;
Other;
Abstract
A pharmaceutical composition useful in the treatment or prevention of transgenic xenograft rejection comprising immunosuppressant compounds selected from the group consisting of an IL-2 transcription inhibitor and immunosuppressant compounds that immunosuppress for B-cell-mediated or antibody-mediated rejection of xenografts, and pharmaceutically acceptable diluents or carriers, and a method of preventing hyperacute rejection, reducing early graft damage, improving early xenograft function and promoting long term survival of said transgenic xenografts comprising the steps of i) contacting the body fluid removed from a human recipient with a xenoantigenic material which is bound to a biocompatible solid support, ii) reintroducing the treated body fluid into the recipient, and iii) treating the recipient with said pharmaceutical composition.