The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 30, 2013
Filed:
Aug. 12, 2010
Raja G. Khalifah, Cary, NC (US);
Roland Keilitz, Erlinsbach, CH;
Christoph Koellner, Liestal, CH;
Thorsten Degenhardt, Raleigh, NC (US);
Stephen Robert Brand, Chapel Hill, NC (US);
Raja G. Khalifah, Cary, NC (US);
Roland Keilitz, Erlinsbach, CH;
Christoph Koellner, Liestal, CH;
Thorsten Degenhardt, Raleigh, NC (US);
Stephen Robert Brand, Chapel Hill, NC (US);
NephroGenex, Inc., Research Triangle Park, NC (US);
Abstract
The invention provides non-oxidative methods for the large scale manufacture of pyridoxamine (I) (4-aminomethyl-3-hydroxy-5-hydroxymethyl-2-methylpyridine): and salts thereof.The invention also provides intermediate compounds for the synthesis of pyridoxamine, as well as compositions and methods for the treatment and/or prevention of conditions associated with the formation of post-Amadori advanced glycation end-products.