IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8431695 B1

PDFFull Text
Date of Patent:
Apr. 30, 2013

Filed:

Nov. 02, 2006

Pyrrolo[2,1-f][1,2,4]triazin-4-ylamines igf-1r kinase inhibitors for the treatment of cancer and other hyperproliferative diseases

Applicants:

Stephen O'connor, Guilford, CT (US);

Jacques Dumas, Carlisle, MA (US);

Wendy Lee, San Ramon, CA (US);

Julie Dixon, Bethany, CT (US);

David Cantin, Hamden, CT (US);

David Gunn, Hamden, CT (US);

Jennifer Burke, Newtown, CT (US);

Barton Phillips, New Haven, CT (US);

Derek Lowe, Acton, MA (US);

Tatiana Shelekhin, Ridgefield, CT (US);

Gan Wang, Wallingford, CT (US);

Xin MA, Haan, DE;

Shihong Ying, Orange, CT (US);

Andrea Mcclure, West Haven, CT (US);

Furahi Achebe, West Haven, CT (US);

Mario Lobell, Wuppertal, DE;

Frederick Ehrgott, Killingworth, CT (US);

Christiana Iwuagwu, Hamden, CT (US);

Kyle Parcella, Wallingford, CT (US);

Inventors:

Stephen O'Connor, Guilford, CT (US);

Jacques Dumas, Carlisle, MA (US);

Wendy Lee, San Ramon, CA (US);

Julie Dixon, Bethany, CT (US);

David Cantin, Hamden, CT (US);

David Gunn, Hamden, CT (US);

Jennifer Burke, Newtown, CT (US);

Barton Phillips, New Haven, CT (US);

Derek Lowe, Acton, MA (US);

Tatiana Shelekhin, Ridgefield, CT (US);

Gan Wang, Wallingford, CT (US);

Xin Ma, Haan, DE;

Shihong Ying, Orange, CT (US);

Andrea McClure, West Haven, CT (US);

Furahi Achebe, West Haven, CT (US);

Mario Lobell, Wuppertal, DE;

Frederick Ehrgott, Killingworth, CT (US);

Christiana Iwuagwu, Hamden, CT (US);

Kyle Parcella, Wallingford, CT (US);

Assignee:

Bayer Intellectual Property GmbH, Monheim, DE;

Attorney:
Primary Examiner:

Venkataraman Balasubramanian

Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 413/02 (2006.01); C07D 417/02 (2006.01); A61K 31/53 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to novel compounds of formula (I). Formula (I) in which the variable groups are as defined in the specification and claims, to pharmaceutical compositions containing them, and to a method of treatment using them for treatment of cancer.

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