The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 30, 2013
Filed:
May. 05, 2011
Applicants:
Victor J. Torres, New York, NY (US);
Ashley L. Dumont, New York, NY (US);
Inventors:
Victor J. Torres, New York, NY (US);
Ashley L. Dumont, New York, NY (US);
Assignee:
New York University, New York, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/12 (2006.01); A61K 39/40 (2006.01);
U.S. Cl.
CPC ...
Abstract
Disclosed herein are isolated and purifiedbi-component leukocidin, referred to herein as LukAB, and its components LukA and LukB, antibodies specific to LukA, antibodies specific to LukB, therapeutic compositions containing LukA and/or LukB, or anti-LukA and/or anti-LukB antibodies, uses of the compositions to treat acute inflammatory conditions orinfection, methods for identifying inhibitors of LukAB-mediated cytotoxicity of human phagocytes, and methods for using LukAB as a marker to predict severity ofinfection.