The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 30, 2013
Filed:
Feb. 16, 2010
Thomas Eugene Christos, Wake Forest, NC (US);
George S. Amato, Cary, NC (US);
Robert N. Atkinson, Raleigh, NC (US);
Maria Graciela Barolli, Morrisville, NC (US);
Lilli Ann Wolf-gouveia, Bahama, NC (US);
Mark J. Suto, Chapel Hill, NC (US);
Thomas Eugene Christos, Wake Forest, NC (US);
George S. Amato, Cary, NC (US);
Robert N. Atkinson, Raleigh, NC (US);
Maria Graciela Barolli, Morrisville, NC (US);
Lilli Ann Wolf-Gouveia, Bahama, NC (US);
Mark J. Suto, Chapel Hill, NC (US);
Icagen Inc., Durham, NC (US);
Abstract
Compounds, compositions and methods are provided which are useful in the treatment of diseases through the modulation of potassium ion flux through voltage-dependent potassium channels. More particularly, the invention provides heterocycles, compositions and methods that are useful in the treatment of central or peripheral nervous system disorders (e.g., migraine, ataxia, Parkinson's disease, bipolar disorders, trigeminal neuralgia, spasticity, mood disorders, brain tumors, psychotic disorders, myokymia, seizures, epilepsy, seizure, retinal degeneration, hearing and vision loss, Alzheimer's disease, age-related memory loss, learning deficiencies, anxiety, neuronal degeneration and motor neuron diseases, maintaining bladder control or treating urinary incontinence) and as neuroprotective agents (e.g., to prevent stroke and the like) by modulating potassium channels associated with the onset or recurrence of the indicated conditions.