The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 30, 2013

Filed:

Feb. 15, 2011
Applicants:

Devi R Gohimukkula, Jamestown, NC (US);

David Robert Jones, Milford, OH (US);

Ghassan Qabaja, Jamestown, NC (US);

Jeff J Zhu, Winston Salem, NC (US);

Jeremy T Cooper, High Point, NC (US);

William K Banner, Greensboro, NC (US);

Kurt Sundermann, Summerfield, NC (US);

Muralidhar Bondlela, Greensboro, NC (US);

Mohan Rao, Greensboro, NC (US);

Pingzhen Wang, Kernersville, NC (US);

Suparna Gupta, Greensboro, NC (US);

Anitha Hari, High Point, NC (US);

Raju B Gowda, Oak Ridge, NC (US);

Robert C Andrews, Jamestown, NC (US);

Inventors:

Devi R Gohimukkula, Jamestown, NC (US);

David Robert Jones, Milford, OH (US);

Ghassan Qabaja, Jamestown, NC (US);

Jeff J Zhu, Winston Salem, NC (US);

Jeremy T Cooper, High Point, NC (US);

William K Banner, Greensboro, NC (US);

Kurt Sundermann, Summerfield, NC (US);

Muralidhar Bondlela, Greensboro, NC (US);

Mohan Rao, Greensboro, NC (US);

Pingzhen Wang, Kernersville, NC (US);

Suparna Gupta, Greensboro, NC (US);

Anitha Hari, High Point, NC (US);

Raju B Gowda, Oak Ridge, NC (US);

Robert C Andrews, Jamestown, NC (US);

Assignee:

TransTech Pharma, Inc., High Point, NC (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/58 (2006.01); A01N 43/60 (2006.01); A61K 31/50 (2006.01); A61K 31/495 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides phenyl-heteroaryl derivatives of Formula (I) and pharmaceutically acceptable salts thereof These compounds are useful in the treatment of RAGE-mediated diseases such as Alzheimer's Disease. The present invention further relates to methods for the preparation of compounds of Formula (I) and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising such compounds, and the use of such compounds and/or pharmaceutical compositions in treating RAGE-mediated diseases.


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