The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 30, 2013
Filed:
Dec. 09, 2008
Jonathan R. Young, Southborough, MA (US);
Jongwon Lim, Boston, MA (US);
Michelle R. Machacek, Brookline, MA (US);
Brandon Mitsuo Taoka, Allston, MA (US);
Ryan D. Otte, Natick, MA (US);
Jonathan R. Young, Southborough, MA (US);
Jongwon Lim, Boston, MA (US);
Michelle R. Machacek, Brookline, MA (US);
Brandon Mitsuo Taoka, Allston, MA (US);
Ryan D. Otte, Natick, MA (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2) and PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3 TYK2 and PDK1 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer.